Our scientific interests are based on both the study of genetic susceptibility to complex diseases, such as melanoma, as well as the understanding of genomic deregulation in solid tumors, specially Breast Cancer in Young Women. We are also involved in the characterization of genetics and epigenetic alterations that play a role in gastric cancer, specifically in the positive subgroups of Epstein Bar virus and instability.
Dr. Ribas joined the Fundacion Investigacion Hospital Clinico Valencia /INCLIVA as Researcher FIS “Miquel Servet” within the Medical Oncology and Hematology Unit in 2009. She received her Ph.D. from the University Autonoma of Barcelona in 1995. She then moved first to the MRC Immnunochemistry from Oxford University UK (1996-1998) and later to the Human Genome Mapping Project Resource Centre (Hinxton,Wellcome Trust campus, Cambridge, UK) (1998-2002). During these two postdoctoral stages she studied molecular biology and participated in the sequencing of the first and now reference human genome, and as Research Associated mastered several genotyping technologies, start-of-the-art at that time (DHPLC, Invader, taqman, mass spectrometry and pyrosequencing). Some of those technologies were acquired through collaborating with Dr. J. Todd (Wellcome Trust Diabetes and Inflammation Laboratory, University of Cambridge). She got used to liquid handling robotics to performed high-throuput assays and learned the use of reagents in microvolums.
She returned to Spain to the Spanish National Cancer Centre (CNIO) as staff scientist in the laboratory of Dr. Javier Benítez (2002-2009) implementing several genotyping technologies for research and diagnostic purposes. Since joining the Human Genetics Lab, Gloria Ribas has focused her interests to the susceptibility of low penetrance genetic variation and their contribution to complex diseases, susceptibility to sporadic breast cancer (since 2002) funded with competitive public national Project (BFI2003-03852) and more recently to cutaneous melanoma (initiated in 2004 with the collaboration to Dr. P. Lázaro, head of Pigment Tumor Unit from the Hospital Gregorio Marañón funded with a competitive national public and private funding agencies (FMMA 2007-SAF2007-65542_C02_01).
She moved again to the Fundación Investigación Clínico de Valencia Instituto de Investigaciones Sanitarias-INCLIVA as Researcher FIS “Miquel Servet” 2009 and successfully renewed the contract to type II on 2015. Dr Ribas is continuing with the genetic susceptibility to melanoma and has managed to secure funding (SAF2009-07072E (2010), and PI10-0405 (2011-2013). She is now participating in other projects of the Medical Oncology and Hematology Unit (Studying the biology of very young breast cancer patients PI13/00606 as IP), and recently join Dr. A. Cervantes’s group, New diagnostic and therapeutic developments in gastrointestinal cancer Group where she is leading a project in gastric cancer, and she is involved with other members of the group in the design and implementation of next generation sequencing of ctDNA in liquid biopsies.