Área Metabolismo

Respiratoy Problems in Neuromuscular Illnesses research group

Jaime Signes-Costa Miñana


•  Evaluate the usefulness of mechanically-assisted coughing techniques with in-exsufflation and high-frequency fluctuations in patients with amyotrophic lateral sclerosis both in medically-stable situations and during respiratory exacerbations. 
•   Identify indicators that allow the inability to maintain spontaneous ventilation in patients with amyotrophic lateral sclerosis (ALS) to be predicted both in clinically-stable situations and during acute exacerbations. 
•  Establish the role of bulbar palsy and the function of non-invasive ventilation failure asynchronies during acute exacerbations in patients with ALS. 
•  Show the effectiveness of an emotional distress psychological intervention program in patients with ALS and their caregivers. 
•  Contribute to work aimed at demonstrating the relevancy of identifying etiological agents in genetic-epidemiological studies of sepsis.