Research Group on Pedriatric Nutrition
Cardiovascular Area
Cardiovascular area:- Study of metabolome and microbiome in obese children with/without insulin resistance before and after personalized nutritional intervention and physical exerciseArea of human milk:
– Characterization of mother-infant microbiome in term and preterm infants. Influence of perinatal variables
Area of hospital malnutrition and artificial nutrition:
– Validation of the pediatric screening tools for detecting the risk of malnutrition linked to chronic disease and pediatric hospitalization
Coordinator
Dr. Cecilia Martínez Costa
cecilia.martinez@uv.es; cmcosta@uv.es
RESEARCHERS
Established, R3
Elena Crehuá GaudizaFrancisco Núñez GómezJavier Estañ CapellJose Vicente Arcos MachancosesLaura Martínez Rodríguez
Recognised/Emerging, R2
Ana Paula GrattarolaJose Luis López PratsPatricia Roselló Millet
First Stage, R1
Alba Peretó MollAna Barrés FernándezÁngel Vicente Valls ArévaloIsidro Robredo GarcíaLaura Núñez MartínezVicente Posadas Blázquez
STAFF
Collaborating Researchers
Inmaculada Tarazona Casany
Nurse
Technicians
Administrative assistant
Publications
Assessment of SARS-CoV-2 neutralizing antibody titers in breastmilk from convalescent and vaccinated mothers. Bauerl C, Zulaica J, Rusu L, Moreno A, Perez-Cano F, Lerin C, Mena-Tudela D, Aguilar-Camprubi L, Parra-Llorca A, Martinez-Costa C, Geller R, Collado M. Iscience. 2023 Jun 16;26(6):106802. doi: 10.1016/j.isci.2023.106802. PMID: 37197591Benefits of paediatric to adult transition programme in inflammatory bowel disease: the BUTTERFLY Study of GETECCU and SEGHNP. De Célix C, Martín-de-Carpi J, Pujol-Muncunill G, Palomino L, Rodríguez-Belvís M, Martín-Masot R, Navas-López V, Ricart E, Casanova M, Rodríguez-Martínez A, Leo-Carnerero E, Alcaraz A, Mañosa M, Hernández V, Cobelas M, Sánchez C, Menchén L, Mesonero F, Barreiro-De Acosta M, Martinón-Torres N, Sandoval C, Váazquez A, Corsino P, Vicente R, Hernández-Camba A, Alonso J, Alonso-Abreu I, Millán A, Reverter L, Castro B, Fernández-Salgado E, Cuiñas M, Benítez J, Madero L, Clemente F, Riestra S, Jiménez-Treviño S, Boscá-Watts M, Crehuáa-Gaudiza E, Moya M, Huguet J, Largo-Blanco E, Vives L, Plaza R, Guerra I, Barrio J, Escartín L, Alfambra E, Cruz N, Muñoz M, Pino M, Van Domselaar M, Botella B, Miquel D, Grau M, De La Mano A, Ber Y, Iñiguez M, Martínez-Pérez T, Chaparro M, Gisbert J. Journal of Clinical Medicine. 2023 Jul 21;12(14):4813. doi: 10.3390/jcm12144813. PMID: 37510928
Breast milk immune composition varies during the transition stage of lactation: characterization of immunotypes in the MAMI cohort. Rio-Aige K, Fernández-Bargalló A, Vegas-Lozano E, Miñarro-Alonso A, Castell M, Selma-Royo M, Martínez-Costa C, Rodríguez-Lagunas M, Collado M, Pérez-Cano F. Frontiers in Nutrition. 2023 Nov 23:10:1252815. doi: 10.3389/fnut.2023.1252815. PMID: 38075221
Culture of human rotaviruses in relevant models shows differences in culture-adapted and nonculture-adapted strains. Peña-Gil N, Randazzo W, Carmona-Vicente N, Santiso-Bellón C, Carcamo-Cálvo R, Navarro-Lleó N, Monedero V, Yebra M, Buesa J, Gozalbo-Rovira R, Rodríguez-Díaz J. International Journal of Molecular Sciences. 2023 Dec 11;24(24):17362. doi: 10.3390/ijms242417362. PMID: 38139191
Differences when classifying small for gestational age preterm infants according to the growth chart applied. Estan Capell J, Alarcon Torres B, Miro Pedro M, Martinez Costa C. American Journal of Perinatology. 2023 Jan 29. doi: 10.1055/s-0043-1761297. PMID: 36709759
Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study. Selma-Royo M, Bauerl C, Mena-Tudela D, Aguilar-Camprubi L, Perez-Cano FJ, Parra-Llorca A, Lerin C, Martinez-Costa C, Collado MC. Genome Medicine. 2022 Apr 21;14(1):42. doi: 10.1186/s13073-022-01043-9. PMID: 35449030BD MAX enteric bacterial, bacterial plus, and virus panels for diagnosis of acute infectious gastroenteritis: a cost-benefit analysis. Ferrer J, Gimenez E, Carretero D, Buesa J, Morillas F, Granell R, Fuenmayor A, Navarro D, Albert E. Microbiology Spectrum. 2022 Oct 26;10(5):e0088022. doi: 10.1128/spectrum.00880-22. PMID: 36069590
Breast milk lipidome is associated with maternal diet and infants’ growth. Calvo-Lerma J, Selma-Royo M, Hervas D, Yang B, Intonen L, Gonzalez S, Martinez-Costa C, Linderborg K, Collado M. Frontiers in Nutrition. 2022 Jul 6;9:854786. doi: 10.3389/fnut.2022.854786. PMID: 35873422
Correlation of anti-tissue transglutaminase antibodies with the mucosal changes and IgA status of children with celiac disease. Donat E, Roca M, Castillejo G, Sanchez-Valverde F, Garcia-Burriel JI, Martinez-Ojinaga E, Eizaguirre FJ, Barrio J, Cilleruelo ML, Perez-Solis D, Ochoa-Sangrador C, Vecino-Lopez R, Miranda-Cid MC, Garcia-Calatayud S, Torres-Peral R, Juste M, Armas H, Barros-Garcia P, Leis R, Solaguren R, Salazar JC, Garcia-Romero R, Ortigosa L, Pena-Quintana L, Urruzuno P, Codoner P, Garcia-Casales Z, Masiques ML, Galicia-Poblet G, Crehua-Gaudiza E, Balmaseda E, Rubio-Santiago J, Polanco-Allue I, Roman-Riechmann E, Ribes-Koninck C. Journal of Pediatric Gastroenterology and Nutrition. 2022 Dec 1;75(6):743-748. doi: 10.1097/MPG.0000000000003620. PMID: 36123770
Cross-cultural adaptation to Spanish and content validity of three nutritional risk scales. Balaguer Lopez E, Garcia-Molina P, Nunez F, Crehua-Gaudiza E, Montal Navarro M, Pedron Giner C, Vitoria Minana I, Jovani Casano C, Galera Martinez R, Gomez-Lopez L, Rodriguez Martinez G, Martinez-Costa C. Anales de Pediatria. 2022 Jul;97(1):12-21. doi: 10.1016/j.anpede.2022.06.001. PMID: 35729061
Adaptive immune responses to SARS-CoV-2 in recovered severe COVID-19 patients. Olea B, Albert E, Torres I, Amat P, Remigia M, Gozalbo-Rovira R, Rodriguez-Diaz J, Buesa J, Blasco M, Redon J, Signes-Costa J, Navarro D. Journal of Clinical Virology. 2021 Sep;142:104943. doi: 10.1016/j.jcv.2021.104943. PMID: 34391981Amplification of human beta-glucoronidase gene for appraising the accuracy of negative SARS-CoV-2 RT-PCR results in upper respiratory tract specimens. Albert Vicent E, Ferrer Lores B, Torres Fink I, Serrano Alcalá A, Alcaráz Soriana M, Buesa Gomez J, Solano Vercet C, Colomina Rodríguez F, Bueno Ferrando F, Huntley Pascual D, Olea Miguel B, Valdivia Piqueres A, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):48-50. doi: 10.1002/jmv.26112. PMID: 32484950
An investigation of the potential association between gastrointestinal viral and bacterial infection and development of intestinal acute graft versus host disease following allogeneic hematopoietic stem cell transplantation. Bueno F, Albert E, Gimenez E, Pinana J, Perez A, Gomez M, Hernandez-Boluda J, Gonzalez-Barbera E, Montoro J, Buesa J, Guerreiro M, Balaguer-Rosello A, Hernani R, Sanz J, Solano C, Navarro D. Journal of Medical Virology. 2021 Aug;93(8):4773-4779. doi: 10.1002/jmv.26892. PMID: 33605457
Breastfeeding practices influence the breast milk microbiota depending on pre-gestational maternal bmi and weight gain over pregnancy. Cortes-Macias E, Selma-Royo M, Martinez-Costa C, Collado MC. Nutrients. 2021 Apr 30;13(5):1518. doi: 10.3390/nu13051518. PMID: 33946343
Case report: primary peritonitis as the onset of pediatric Menetrier’s disease. Barres-Fernandez A, Piolatti-Luna A, Breton-Martinez J, Crehua-Gaudiza E, Quinones-Torrelo C, Moscardo-Navarro A, Fuertes-Latasa C, Martinez-Costa C. Frontiers in Pediatrics. 2021 Jan 13;8:589853. doi: 10.3389/fped.2020.589853. PMID: 33520889
Projects
Title: NEODIAG-VR: Realidad virtual para la formación multidisciplinar en neonatología
Funding body: Universidad de Valencia – INCLIVA
Principal Investigator: Jesús Gimeno Sancho, Javier Estañ Capell
Duration: 2021 – 2022
Total budget: 4.655 €
Title: Efectividad de la vacunación antigripal y antineumocócica para prevenir la hospitalización en personas menores de 65 años que presentan condiciones de riesgo
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Ángela Domínguez García
Duration: 2020 – 2022
Total budget: 220.220 €
Title: Evaluación de una intervención basada en la evidencia para reducir la bacteriemia asociada a catéter vascular central en recién nacidos de muy bajo peso (RNMBP)
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Jose Ignacio Pijaón Zubizarreta
Duration: 2018 – 2020
Total budget: 146.108 €
Title: Obesidad materna y disfunción cognitiva en la descendencia: papel causa-efecto de la microbiota intestinal y prevención dietética temprana
Funding body: Ministerio de Economía y Competitividad
Principal Investigator: Consuelo Borrás Blasco
Duration: 2017 – 2022
Total budget: 143.000 €
Title: GUTMOM: Maternal obesity and cognitive dysfunction in the offspring: cause-effect role of the GUT MicrobiOMe and early dietary prevention
Funding body: European Commission. JPI HDHL
Principal Investigator: Patricia Lozzo
Duration: 2017 – 2020
Total budget: 778.240 €
Title: Diversidad genética y antigénica de norovirus humanos: estudio de anticuerpos séricos protectores y de la inmunidad celular en ratones y en pacientes infectados
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Buesa Gómez
Duration: 2017 – 2019
Total budget: 68.365 €
Title: MAMI – The Power of Maternal Microbes on Infant Health
Funding body: European Commission
Principal Investigator: María Carmen Collado
Duration: 2015 – 2020
Total budget: 1.499.978 €
+ Info
Doctoral candidate: Balaguer López, Evelin
Director(s): Martínez Costa, Cecilia; Núñez Gómez, Francisco
Date of the defense: 24/02/2023
University: Universitat de ValènciaTitle: Estudio del desarrollo y la función renal, y de aspectos implicados en el síndrome metabólico del adulto, en gemelos con peso dispar al nacimiento. Valoración durante la edad pediátrica
Doctoral candidate: Marín Serra, Juan
Director(s): Hernández Marco, Roberto; Núñez Gómez, Francisco; Fons Moreno, Jaime
Date of the defense: 24/10/2022
University: Universitat de ValènciaTitle: Anomalías craneofaciales y dentales en una población de escolares nacidos pretérmino
Doctoral candidate: Peiró Guijarro, María Aurora
Director(s): Martínez Costa, Cecilia; Catalá Picarro, Montserrat; Martínez Rodríguez, Laura
Date of the defense: 25/03/2022
University: Universitat de València
Title: Efecto de la intervención nutricional en escolares y adolescentes con obesidad con y sin resistencia a la insulina
Doctoral candidate: Grattarola, Ana Paula
Director(s): Núñez Gómez, Francisco; Martínez Costa, Cecilia
Date of the defense: 11/01/2021
University: Universitat de València
Title: Aproximaciones moleculares al estudio de las interacciones de rotavirus y norovirus con el huésped
Doctoral candidate: Vila Vicent, Susana
Director(s): Rodríguez Díaz, Jesús; Buesa Gómez, Francisco Javier
Date of the defense: 05/11/2020
University: Universitat de València
Title: Aplicación de la termografía infrarroja en pediatría: análisis de las alteraciones de la microcirculación cutánea
Doctoral candidate: Benavent Casanova, Olga
Director(s): Núñez Gómez, Francisco; Cibrián Ortíz De Anda, Rosa; Salvador Palmer, María Rosario
Date of the defense: 23/07/2020
University: Universitat de València
Title: Antígenos histo-sanguíneos e infección por rotavirus
Doctoral candidate: Pérez Ortín, Raúl
Director(s): Buesa Gómez, Francisco Javier
Date of the defense: 15/01/2020
University: Universitat de València