Dr. José Mª Vila Salinas

Principal Investigator
Research Group on Vascular Function

Presentation

Dr. Vila, University Professor in the Department of Physiology, holds a degree and a PhD in Pharmacy from the University of Valencia. He teaches in the degrees of Pharmacy, Medicine, Dentistry and Podiatry and in the master’s degree of Physiology. His research is developed in the field of cardiovascular physiology. The main areas of interest focus on the mechanisms of circulation regulation, mainly those involved in vascular function. Current topics of work revolve around the role of the endothelium in cardiometabolic diseases such as obesity, type II diabetes and hypertension; the use of nanoparticles in the field of medicine and the study of the protective anti-inflammatory and antioxidant effect of medicine. These lines of research have been supported by more than 20 research projects in which he has participated as a collaborating researcher or principal investigator. He is co-author of a hundred articles in international journal and has supervised more than 20 doctoral theses.

Dr. José Mª Vila Salinas
Principal
Investigator
Dr. José Mª Vila Salinas

jose.m.salinas@uv.es

Publications
Effects of GLP-1 receptor agonists on mitochondrial function, inflammatory markers and leukocyte-endothelium interactions in type 2 diabetes. Luna-Marco C, de Maranon A, Hermo-Argibay A, Rodriguez-Hernandez Y, Hermenejildo J, Fernandez-Reyes M, Apostolova N, Vila J, Sola E, Morillas C, Rovira-Llopis S, Rocha M, Victor V. Redox Biology. 2023 Aug 14;66:102849. doi: 10.1016/j.redox.2023.102849. PMID: 37591012

Improvement of vascular insulin sensitivity by ranolazine. Guerra-Ojeda S, Jorda A, Aldasoro C, Vila J, Valles S, Arias-Mutis O, Aldasoro M. International Journal of Molecular Sciences. 2023 Aug 31;24(17):13532. doi: 10.3390/ijms241713532. PMID: 37686345

Cerium dioxide nanoparticles modulate antioxidant defences and change vascular response in the human saphenous vein. Guerra-Ojeda S, Marchio P, Rueda C, Suarez A, Garcia H, Victor V, Juez M, Martin-Gonzalez I, Vila J, Mauricio M. Free Radical Biology & Medicine. 2022 Nov 17;193(Pt 2):694-701. doi: 10.1016/j.freeradbiomed.2022.11.012. PMID: 36402438

Deleterious effects of levamisole, a cocaine adulterant, in rabbit aorta. Guerra-Ojeda S, Marchio P, Aldasoro M, Valles S, Genoves P, Mauricio M, Vila J. Vascular Pharmacology. 2022 Jun;144:106992. doi: 10.1016/j.vph.2022.106992. PMID: 35358704

Facilitation of insulin effects by ranolazine in astrocytes in primary culture. Jorda A, Aldasoro M, Campo-Palacio I, Vila JM, Aldasoro C, Campos-Campos J, Colmena C, Singh SK, Obrdor E, Valles SL. International Journal of Molecular Sciences. 2022 Oct 9;23(19):11969. doi: 10.3390/ijms231911969. PMID: 36233271

Ischemia-reperfusion injury to coronary arteries: comprehensive microscopic study after reperfused myocardial infarction. Rios-Navarro C, Daugbouche-Rubio N, Gavara J, de Dios E, Perez N, Vila JM, Chorro FJ, Ruiz-Sauri A, Bodi V. Annals of Anatomy. 2021 Nov;238:151785. doi: 10.1016/j.aanat.2021.151785. PMID: 34144157

Overexpression of genes involved in lymphocyte activation and regulation are associated with reduced CRM-derived cardiac remodelling after STEMI. de Dios E, Rios-Navarro C, Perez-Sole N, Gavara J, Marcos-Garces V, Forteza M, Oltra R, Vila J, Chorro F, Bodi V. International Immunopharmacology. 2021 Mar 4;95:107490. doi: 10.1016/j.intimp.2021.107490. PMID: 33677257

PPARgamma as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits. Guerra-Ojeda S, Marchio P, Gimeno-Raga M, Arias-Mutis O, San-Miguel T, Valles S, Aldasoro M, Vila J, Zarzoso M, Mauricio M. Atherosclerosis. 2021 Aug 5;332:16-23. doi: 10.1016/j.atherosclerosis.2021.08.006. PMID: 34375909

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

+ Info
Title: Interacciones de la ranolazina con agentes vasoactivos endógenos y exógenos.
Doctoral candidate: Campos Carot, Elena
Director(s): Vila Salinas, José Mª; Mauricio Aviñó, Mª Dolores; Martínez León, Juan B
Date of the defense: 19/12/2022
University: Universitat de València