Research Group on the Study of Cardiometabolic and Renal Risk
Cardiovascular Area
To start-up the laboratory for the analysis of podocytes (identification, cultivation and phenotyping) and its derivatives: micro-RNA, exosomes
To identify a circulating and exosomal non-coding RNA – mRNA interaction networks associated to renal damage progression
The integration of metabolomics and genomics in the study of factors related to the development of kidney damage
Development of studies for noninvasive hemodynamic characterization in vascular pathology
Analysis of morbidity and mortality linked to the presence of hypertension and renal injury
Development of in vitro studies of platelet and leukocyte adhesion in venous thromboembolism
Genetic studies related to obesity and overweight and venous thromboembolism
Development of phase III and IV clinical trials
Characterize the cardiovascular risk and alterations in renal function in patients with HIV infection and in HIV/HBV-HCV co-infected
Assess the comorbidities of patients with HIV and their impact on the development of frailty and quality of life
Assess the risk of impaired kidney function in people on PrEP
Determine the cardiovascular risk and alterations in renal function in patients with HIV infection
Analyze the comorbidities of patients with HIV infection and their impact on the development of frailty and quality of life
Characterize the natural history of viral hepatitis: study of factors related to the development of cardiometabolic damage and development of clinical events
Develop biomarkers to diagnose and predict the development of clinical events in patients with HIV infection, viral hepatitis and other infectious pathologies
Assess the risk of impaired renal function in people on PrEP and its management
Develop interventions for primary and secondary prevention in this context: microelimination strategies, early diagnosis and personalized patient management
Coordinator
STAFF
Collaborating Researchers
Elena Solaz MorenoJavier Díaz Carnicero
Nurse
Technicians
Antonio Fernández GiménezMarta Méndez DebaetsNoemí Dolz Gilba
Administrative assistant
Publications
MASLD biomarkers: are we facing a new era?. Maya-Miles D, Ampuero J, Marti-Aguado D, Conthe A, Gallego-Duran R. Gastroenterologia y Hepatologia. 2024 Feb 12:S0210-5705(24)00053-0. doi: 10.1016/j.gastrohep.2024.02.004. PMID: 38355096
Perspectives of people with HIV and HIV clinicians on characteristics of antiretroviral treatment and HIV-related symptoms. Puerto M, Puig J, Pérez-Molina J, de Apodaca M. HIV Medicine. 2024 Jan 12. doi: 10.1111/hiv.13609. PMID: 38214438
Real-life data of immune recovery using bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed people living with HIV. Results at 48-96 weeks of RETROBIC Study. Troya J, Pousada G, Micán R, Galera C, Sanz J, de Los Santos I, Dueñas C, Cabello N, Martín C, Galindo MJ, Garcinuño MÁ, Pedrero-Tomé R, Buzón L. Journal of Antimicrobial Chemotherapy. 2024 Jan 24:dkae011. doi: 10.1093/jac/dkae011. PMID: 38267266
Acquired aggressive multisystemic disseminated lobular capillary haemangioma: a life threatening disorder. Monteagudo C, Porcar-Saura S, Navarro S, Burgues O, Gonzalez J, Ferrandez A, Forner M. Pathology. 2023 Aug;55(5):729-732. doi: 10.1016/j.pathol.2022.11.014. PMID: 36894353
All-cause hospitalisation among people living with HIV according to gender, mode of HIV acquisition, ethnicity, and geographical origin in Europe and North America: findings from the ART-CC cohort collaboration. Rein S, Lampe F, Ingle S, Sterne J, Trickey A, Gill M, Papastamopoulos V, Wittkop L, van der Valk M, Kitchen M, Guest J, Satre D, Wandeler G, Galindo P, Castilho J, Crane H, Smith C. Lancet. Public Health. 2023 Oct;8(10):e776-e787. doi: 10.1016/S2468-2667(23)00178-0. PMID: 37777287
Association of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: the national health and nutrition examination survey 1999-2018. Gonzalez-Martin R, Grau-Perez M, Sebastian-Leon P, Diaz-Gimeno P, Vidal C, Tellez-Plaza M, Dominguez F. Environmental Research. 2023 Sep 15:233:116514. doi: 10.1016/j.envres.2023.116514. PMID: 37392826
Association of single and joint metals with albuminuria and estimated glomerular filtration longitudinal change in middle-aged adults from Spain: The Aragon workers health study. Grau-Perez M, Domingo-Relloso A, Garcia-Barrera T, Gomez-Ariza J, Leon-Latre M, Casasnovas J, Moreno-Franco B, Laclaustra M, Guallar E, Navas-Acien A, Pastor-Barriuso R, Redon J, Tellez-Plaza M. Environmental Pollution. 2023 Feb 1;318:120851. doi: 10.1016/j.envpol.2022.120851. PMID: 36509352
A comprehensive urban programme to reduce energy poverty and its effects on health and wellbeing of citizens in six European countries: study protocol of a controlled trial. Stevens M, Raat H, Ferrando M, Vallina B, Lucas R, Middlemiss L, Redon J, Rocher E, van Grieken A. BMC Public Health. 2022 Aug 19;22(1):1578. doi: 10.1186/s12889-022-13968-2. PMID: 35986259
Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. Henkens M, Raafs A, Verdonschot J, Linschoten M, van Smeden M, Wang P, van der Hooft B, Tieleman R, Janssen M, ter Bekke R, Hazebroek M, van der Horst I, Asselbergs F, Magdelijns F, Heymans S. BMC Geriatrics. 2022 Mar 5;22(1):184. doi: 10.1186/s12877-021-02673-1. PMID: 35247983
Angiotensin receptor blockers evaluated by office and home blood pressure measurements. TeleHBPM Study. Barroso Weimar Kunz Sebba, Brandao AA, Valverde de Oliveira Vitorino P, Diogenes de Magalhaes Feitosa A, Costa Duarte Barbosa E, Dischinger Miranda R, Redon J, Camafort-Babkowski M, Coca A, Mota Gomes MA. Arquivos Brasileiros de Cardiologia. 2022 May 9;118(6):1069-1082. doi: 10.36660/abc.20210504. PMID: 35544853
Association between exercise frequency with renal and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk. Bohm M, Schumacher H, Werner C, Teo K, Lonn E, Mahfoud F, Speer T, Mancia G, Redon J, Schmieder R, Sliwa K, Marx N, Weber M, Laufs U, Williams B, Yusuf S, Mann J. Cardiovascular Diabetology. 2022 Jan 20;21(1):12. doi: 10.1186/s12933-021-01429-w. PMID: 35057807
Adaptive immune responses to SARS-CoV-2 in recovered severe COVID-19 patients. Olea B, Albert E, Torres I, Amat P, Remigia M, Gozalbo-Rovira R, Rodriguez-Diaz J, Buesa J, Blasco M, Redon J, Signes-Costa J, Navarro D. Journal of Clinical Virology. 2021 Sep;142:104943. doi: 10.1016/j.jcv.2021.104943. PMID: 34391981
Analysis of LDL and HDL size and number by nuclear magnetic resonance in a healthy working population: the LipoLab Study.. Pallares-Carratala V, Quesada J, Orozco-Beltran D, Amigo-Grau N, Lopez-Pineda A, Fernandez Gimenez A, Gil-Guillen V, Correig X, Masana L, Monleon Salvado D, Redón Mas J, Pascual R, Carratala-Munuera C. International Journal of Clinical Practice. 2021 Jan;75(1):e13610. doi: 10.1111/ijcp.13610. PMID: 32648987
Anthropometric indicators as a tool for diagnosis of obesity and other health risk factors: a literature review. Piqueras P, Ballester A, Dura-Gil J, Martinez-Hervas S, Redon J, Real J. Frontiers in Psychology. 2021 Jul 9;12:631179. doi: 10.3389/fpsyg.2021.631179. PMID: 34305707
Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The Hortega study. Galvez-Fernandez M, Grau-Perez M, Garcia-Barrera T, Ramirez-Acosta S, Gomez-Ariza J, Perez-Gomez B, Galan-Labaca I, Navas-Acien A, Redon J, Briongos-Figuero L, Duenas-Laita A, Perez-Castrillon J, Tellez-Plaza M, Martin-Escudero J. Free Radical Biology & Medicine. 2021 Jan;162:392-400. doi: 10.1016/j.freeradbiomed.2020.10.318. PMID: 33137469
Projects
Title: 101083002- INNDIH – Valencia Region Digital Innovation Hub
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2025
Total budget: 225.395,50 €
Title: Personalised pharmacometabolomic optimisation of treatment for hypertension
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2026
Total budget: 400.000 €
Title: Creación de una plataforma abierta de acceso, captura, almacenamiento e intercambio descentralizado de los datos de salud en tiempo real del Departamento de Salud Clínico-Malvarrosa para la computación cloud-edge de sistemas predictivos, de toma de decisiones y de inteligencia artificial
Funding body: Ministerio de Asuntos Económicos y Transformación Digital
Principal Investigator: Josep Redón i Mas
Duration: 2023 – 2025
Total budget: 5.252.274 €
Title: EHDEN. Harmonization Fund Holder
Funding body: European Commission (3rd Health Program)
Principal Investigator: Josep Redón i Mas
Duration: 2022 – 2023
Total budget: 50.000,00 €
Title: Identificación de ARN no codificantes en biopsia líquida con énfasis en exosomas como biomarcadores pronóstico de actividad en el lupus eritematoso sistémico. Implicación fisiopatológica en el daño renal
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Raquel Cortés Vergaz, Mª José Forner Giner
Duration: 2022 – 2024
Total budget: 135.520 €
Title: WELLBASED. Improving health, wellbeing and equality by evidenced-based urban policies for tackling energy poverty
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2021 – 2025
Total budget: 395.250,00 €
Title: Implicaciones experimentales y clinicas del complejo proteico rabphilin-rab en daño renal en la diabetes mellitus tipo 2
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2020 – 2023
Total budget: 196.020 €
Title: Perfil de microRNAs exosomales y su valor pronostico a largo plazo en el lupus eritematoso sistemico. Asociacion con marcadores establecidos de daño renal
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Raquel Cortés Vergaz, Maria José Forner
Duration: 2019 – 2021
Total budget: 111.320 €
Title: Big Data for Medical Analytics
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 1.062.136 €
Title: Plataforma de Innovación
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 38.985 €
Title: API-ecosystem for cross-sectorial exchange of 3D personal data
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2018 – 2021
Total budget: 351937,5
Title: Estudio experimental in vivo e in vitro y la aplicación clínica del impacto de las proteínas del complejo Rhabphilin-Rab en el desarrollo del daño renal y cardiovascular
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Josep Redón i Mas
Duration: 2017 – 2019
Total budget: 194.205 €
Title: Big Data for Better Hearts
Funding body: European Commission
Principal Investigator: Josep Redón i Mas
Duration: 2017 – 2022
Total budget: 386250
Title: Managing Frailty. A comprehensive approach to promote a disability-free advanced age in Europe: the ADVANTAGE initiative
Funding body: European Commission (3rd Health Program)
Principal Investigator: Josep Redón i Mas, José Viña Ribes
Duration: 2016 – 2019
Total budget: 130.005 €
Title: Innovación tecnológica en la evaluación del sistema nervioso simpático en adolescentes y adultos jóvenes obesos: papel en la estratificación del riesgo e intervención terapéutica
Funding body: Conselleria de Educación, Cultura y Deporte
Principal Investigator: Josep Redón i Mas
Duration: 2016 – 2019
Total budget: 246.190 €
+ Info
2022 Practice guidelines for the management of arterial hypertension of the Spanish Society of Hypertension. Gorostidi M, Gijón-Conde T, de la Sierra A, Rodilla E, Rubio E, Vinyoles E, Oliveras A, Santamaría R, Segura J, Molinero A, Pérez-Manchón D, Abad M, Abellán J, Armario P, Banegas JR, Camafort M, Catalina C, Coca A, Divisón JA, Domenech M, Martell N, Martín-Rioboó E, Morales-Olivas F, Pallarés V, Pérez de Isla L, Prieto MA, Redón J, Ruilope LM, García-Donaire JA. Hipertensión y Riesgo Vascular. 2022 Oct-Dec;39(4):174-194. doi: 10.1016/j.hipert.2022.09.002. PMID: 36153303
Redefining hypertension in children and adolescents: A review of the evidence considered by the European Society of Hypertension and American Academy of Pediatrics guidelines.Stabouli S, Redón Mas J, Lurbe Ferrer E. Journal of Hypertension. 2020 Feb;38(2):196-200. doi: 10.1097/HJH.0000000000002247. PMID: 31584513
2018 ESC/ESH Guidelines for the management of arterial. Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I. Kardiologia Polska. 2019;77(2):71-159. doi: 10.5603/KP.2019.0018. PMID: 30816983
Impact of ESH and AAP hypertension guidelines for children and adolescents on office and ambulatory blood pressure-based classifications. Lurbe E, Torró I, Álvarez J, Aguilar F, Mancia G, Redon J, Redon P. Journal of Hypertension. 2019 Dec;37(12):2414-2421. doi: 10.1097/HJH.0000000000002229. PMID: 31688292
Doctoral candidate: Ruiz Hernández, Adrián
Director(s): Forner Giner, Mª José; Redón i Mas, Josep
Date of the defense: 28/04/2022
University: Universitat de València
Title: Monitorización del manejo de sepsis para la identificación de flujos asistenciales y su impacto en la evolución de los pacientes. El diagnóstico precoz de sepsis en urgencias
Doctoral candidate: Clar Bononad, Jorge
Director(s): Oltra Sempere, Mª Rosa; Redón i Mas, Josep
Date of the defense: 10/02/2022
University: Universitat de València
Title: Estudio prospectivo multicéntrico de precisión diagnóstica de los biomarcadores de imagen en las hepatopatías crónicas difusas
Doctoral candidate: Martí Aguado, David
Director(s): Martí Bonmatí, Luis; Serra Desfilis, Miguel Ángel
Date of the defense: 29/06/2021
University: Universitat de València
Title: Valor pronóstico de los cambios en la rigidez arterial en la hipertensión arterial esencial
Doctoral candidate: Calaforra Juan, Oscar
Director(s): Redón Mas, Josep; Forner Giner, María José; Martínez García, Fernando
Date of the defense: 28/07/2020
University: Universitat de València
Title: Sistema de biosensado fotónico para la detección de trombina, alérgenos y patógenos. Funcionalización química de chips fotónicos basados en estructuras de anillos resonantes
Doctoral candidate: Sánchez Sánchez, Carlos
Director(s): Martí Sendra, Javier; Redón Mas, Josep; Peransí Llopis, Sergio Manuel
Date of the defense: 15/11/2019
University: Universitat Politècnica de València
Title: Estudio de la evolución del sellado distal ilíaco en el tratamiento endovascular de la aorta abdominal
Doctoral candidate: Bargay Juan, Pau
Director(s): Redon Mas, Josep; Plaza Martínez, Ángel
Date of the defense: 25/02/2019
University: Universitat de València